Thomas Hedner Selected Research

Diltiazem (Cardizem)

8/2013	Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
2/2011	A functional variant of the NEDD4L gene is associated with beneficial treatment response with β-blockers and diuretics in hypertensive patients.
4/2009	The myocardial infarction associated CDKN2A/CDKN2B locus on chromosome 9p21 is associated with stroke independently of coronary events in patients with hypertension.
7/2008	Interaction between renal function and microalbuminuria for cardiovascular risk in hypertension: the nordic diltiazem study.
6/2002	Influence of age, sex and blood pressure on the principal endpoints of the Nordic Diltiazem (NORDIL) Study.
1/2002	Comparison of home and office blood pressure in treated hypertensives in the Nordic Diltiazem (NORDIL) Study.

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Thomas Hedner Research Topics

Disease

16	Hypertension (High Blood Pressure) 06/2014 - 01/2000
5	Myocardial Infarction 01/2015 - 06/2002
4	Cardiovascular Diseases (Cardiovascular Disease) 10/2016 - 02/2011
4	Essential Hypertension 08/2013 - 01/2002
3	Coronary Artery Disease (Coronary Atherosclerosis) 01/2015 - 02/2008
3	Neoplasms (Cancer) 07/2013 - 10/2010
3	Stroke (Strokes) 01/2006 - 06/2002
2	Heart Failure 01/2016 - 12/2012
2	Atherosclerosis 04/2014 - 02/2008
2	Inflammation (Inflammations) 02/2008 - 01/2004
2	Diabetes Mellitus 01/2006 - 03/2004
1	Infarction (Infarctions) 01/2015
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 01/2015
1	Orthostatic Hypotension (Postural Hypotension) 01/2014
1	Obesity 07/2013
1	Substance-Related Disorders (Drug Abuse) 07/2013
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2013
1	Type 2 Diabetes Mellitus (MODY) 02/2008
1	Erythema 03/2006
1	Edema (Dropsy) 03/2006
1	Atrophy 03/2006
1	Atopic Dermatitis (Atopic Eczema) 01/2006
1	Hemolytic Anemia 01/2006
1	Heart Diseases (Heart Disease) 01/2006
1	Osteoarthritis 01/2004
1	Atrial Fibrillation 01/2004
1	Rheumatoid Arthritis 01/2004
1	Arthritis (Polyarthritis) 01/2004
1	Pain (Aches) 01/2004
1	Soft Tissue Injuries (Soft Tissue Injury) 01/2004
1	Isolated Systolic Hypertension 01/2004
1	Ankylosing Spondylitis 01/2004
1	Cough 06/2002

Drug/Important Bio-Agent (IBA)

7	DiureticsIBA 01/2016 - 01/2002
7	Antihypertensive Agents (Antihypertensives)IBA 08/2013 - 01/2000
6	Diltiazem (Cardizem)FDA LinkGeneric 08/2013 - 01/2002
6	CalciumIBA 04/2009 - 01/2000
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2005 - 01/2000
2	Captopril (Capoten)FDA LinkGeneric 01/2014 - 03/2004
2	SodiumIBA 02/2011 - 10/2010
2	Angiotensin Receptor AntagonistsIBA 10/2010 - 01/2009
2	Therapeutic UsesIBA 03/2006 - 01/2004
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2005 - 01/2000
1	Actins (F Actin)IBA 01/2015
1	Proteins (Proteins, Gene)FDA Link 01/2015
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2015
1	Biological ProductsIBA 04/2014
1	Pharmaceutical PreparationsIBA 08/2013
1	Protein Kinase CIBA 08/2013
1	Hydrochlorothiazide (Esidrix)FDA LinkGeneric 08/2013
1	Sodium Chloride Symporter Inhibitors (Diuretics, Thiazide)IBA 08/2013
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 07/2013
1	N 30IBA 07/2013
1	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 01/2013
1	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2013
1	P-2 (P 2)IBA 01/2013
1	LipidsIBA 01/2013
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 12/2012
1	Neprilysin (Neutral Endopeptidase)IBA 12/2012
1	Renin InhibitorsIBA 10/2012
1	ReninIBA 02/2011
1	Vasodilator Agents (Vasodilators)IBA 02/2011
1	UromodulinIBA 10/2010
1	DNA (Deoxyribonucleic Acid)IBA 04/2009
1	Cytokine Receptor gp130IBA 02/2008
1	Interleukin-6 (Interleukin 6)IBA 02/2008
1	Triglycerides (Triacylglycerol)IBA 02/2008
1	LDL Lipoproteins (beta Lipoproteins)IBA 02/2008
1	LDL CholesterolIBA 02/2008
1	HDL LipoproteinsIBA 02/2008
1	oxidized low density lipoproteinIBA 02/2008
1	HDL CholesterolIBA 02/2008
1	3,3',5-triiodothyroacetic acid (Triac)IBA 03/2006
1	Thyroid HormonesIBA 03/2006
1	Tretinoin (Retinoic Acid)FDA LinkGeneric 03/2006
1	GlucocorticoidsIBA 03/2006
1	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2006
1	pentaneIBA 01/2006
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2006
1	CholesterolIBA 03/2004
1	Glucose (Dextrose)FDA LinkGeneric 03/2004
1	Estrogens (Estrogen)FDA Link 03/2004
1	Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA 03/2004
1	LeptinIBA 01/2004
1	Analgesics (Analgesic Drugs)IBA 01/2004
1	Nabumetone FDA LinkGeneric 01/2004
1	BradykininIBA 06/2002

Therapy/Procedure

8	Therapeutics 08/2013 - 01/2004
1	Secondary Prevention 10/2016
1	Denervation 06/2014
1	Home Nursing (Nursing, Home) 01/2006
1	Long-Term Care 01/2006